Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HBB | P68871 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631354 | 0.85 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9630379 | 0.84 | MAPT (0.58) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9807629 | 0.80 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13979310 | 0.80 | KDM4E (0.70) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29963695 | 0.80 | ALDH1A1 (0.75) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29360167 | 0.80 | ALDH1A1 (0.75) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL151563 | 0.80 | ALDH1A1 (0.75) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Lindane SCHEMBL9754163 | 0.79 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14805532 | 0.79 | MAPT (0.69) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31027168 | 0.79 | MAPT (0.69) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |