Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838722 | 1.00 | TYR (0.44) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL3429791 | 0.86 | HSD17B3 (0.44) | TYRTRIM24TRIM33ESR1ESR2 | |
| Methyl Alcohol SCHEMBL27892221 | 0.85 | HSD17B3 (0.43) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL3431324 | 0.83 | TYR (0.56) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL29951036 | 0.83 | SRC (0.44) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL6898737 | 0.83 | SRC (0.44) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL5527536 | 0.83 | TYR (0.40) | TYRTRIM24TRIM33ESR1ESR2 | |
| SCHEMBL3427353 | 0.82 | ALOX5 (0.56) | TYRESR1 | |
| SCHEMBL11769499 | 0.82 | TTR (0.41) | TYRTRIM24TRIM33ERN1ALDH5A1 | |
| SCHEMBL5382204 | 0.82 | ESR1 (0.42) | TYRESR1ESR2ESRRBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |