Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957247 | 0.85 | HSD17B10 (0.60) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL13303843 | 0.85 | HSD17B10 (0.60) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL17446897 | 0.81 | HSD17B10 (0.60) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL29954598 | 0.78 | ALDH1A1 (0.60) | HSD17B10ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL10966874 | 0.78 | ALDH1A1 (0.60) | HSD17B10ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL29950854 | 0.78 | ALDH1A1 (0.56) | HSD17B10KMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL14744354 | 0.76 | HSD17B10 (0.53) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL29494947 | 0.76 | HSD17B10 (0.53) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL85918 | 0.76 | HSD17B10 (1.00) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL29360183 | 0.76 | HSD17B10 (1.00) | HSD17B10VCAM1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |