Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12419297 | 1.00 | RECQL (0.60) | RECQLSCN9AERBB2EGFRBRD4 | |
| SCHEMBL29955349 | 0.82 | RECQL (0.69) | RECQLBRD4MEN1CYP1A2RAB9A | |
| SCHEMBL29953781 | 0.82 | RECQL (0.63) | RECQLERBB2EGFRBRD4CYP1A2 | |
| SCHEMBL17602113 | 0.81 | RECQL (0.66) | RECQLSCN9AERBB2EGFRBRD4 | |
| SCHEMBL22533582 | 0.80 | PLA2G4A (0.45) | RECQLSCN9AERBB2EGFRKMO | |
| SCHEMBL29424876 | 0.80 | PLA2G4A (0.45) | RECQLSCN9AERBB2EGFRKMO | |
| SCHEMBL4951910 | 0.79 | RECQL (0.64) | RECQLSCN9AERBB2EGFRBRD4 | |
| SCHEMBL4251433 | 0.79 | HTR2A (0.39) | SLC5A2CA1CA2KMO | |
| SCHEMBL870390 | 0.78 | RECQL (0.66) | RECQLSCN9AERBB2EGFRBRD4 | |
| SCHEMBL1129158 | 0.78 | RECQL (0.66) | RECQLSCN9AERBB2EGFRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |