Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913737 | 1.00 | TRIM24 (0.47) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL6124209 | 0.86 | ESR2 (0.42) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL4940592 | 0.83 | CA12 (0.41) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL8746740 | 0.83 | KDM4E (0.50) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL29216333 | 0.83 | TYR (0.43) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL11900260 | 0.83 | TYR (0.43) | TRIM24TRIM33TYRALDH5A1ABAT | |
| SCHEMBL30335110 | 0.82 | TYR (0.61) | TRIM24TRIM33TYRMEN1KMT2A | |
| SCHEMBL93513 | 0.82 | TYR (0.61) | TRIM24TRIM33TYRMEN1KMT2A | |
| SCHEMBL27645627 | 0.82 | TYR (0.61) | TRIM24TRIM33TYRMEN1KMT2A | |
| SCHEMBL36835 | 0.82 | ERN1 (0.61) | TRIM24TRIM33TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |