Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913737 | 0.83 | TRIM24 (0.47) | ALDH5A1ABATEGFRKDM4EALDH1A1 | |
| SCHEMBL29952866 | 0.83 | TRIM24 (0.47) | ALDH5A1ABATEGFRKDM4EALDH1A1 | |
| SCHEMBL346026 | 0.82 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17057608 | 0.77 | CA14 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3677559 | 0.77 | CA14 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL135290 | 0.76 | TDP1 (0.40) | ALDH1A1POLBMAPTPKMTDP1 | |
| SCHEMBL9404722 | 0.76 | TDP1 (0.48) | KDM4EALDH1A1POLBMAPTTDP1 | |
| SCHEMBL36835 | 0.76 | ERN1 (0.61) | EGFRKDM4EALDH1A1POLBGAA | |
| Formamide SCHEMBL28912568 | 0.76 | ERN1 (0.55) | EGFRKDM4EALDH1A1POLBGAA | |
| SCHEMBL28385480 | 0.74 | ALDH1A1 (0.43) | ALDH5A1ABATKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114999711-A | Stain-resistant cable and preparation method thereof | 赵琳 | 2022-09-02 | — | — | CN | claimed |
| CN-113620875-B | 3-nitrile quinoline derivative and preparation method thereof | 郑州大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114999711-A | Stain-resistant cable and preparation method thereof | 赵琳 | 2022-09-02 | — | — | CN | disclosed |
| CN-114999711-A | Stain-resistant cable and preparation method thereof | 赵琳 | 2022-09-02 | — | — | CN | disclosed |
| CN-113620875-A | 3-cyano quinoline derivative and preparation method thereof | 郑州大学 | 2021-11-09 | — | — | CN | disclosed |
| WO-2012051659-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-04-26 | — | — | WO | disclosed |
| EP-1309569-B1 | N-aryl-{4-[7-(alkoxy)quinazolin-4-yl]piperazinyl}carboxamide derivatives as PDGFRs inhibitors | MILLENNIUM PHARM INC (US) | 2010-10-06 | — | — | EP | disclosed |
| US-7612225-B2 | Crystal of triterpene derivative | SHIONOGI & CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612225-B2 | Crystal of triterpene derivative | SHIONOGI & CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| CN-1070183-C | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1215725-A | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1041938-C | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO (JP) | 1999-02-03 | — | — | CN | disclosed |
| EP-0682009-B1 | Intermediate compounds for preparing endothelin-receptor antagonist triterpene derivatives | SHIONOGI & CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5587505-A | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0628569-B1 | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0682009-A2 | Intermediate compounds for preparing endothelin-receptor antagonist triterpene derivatives | SHIONOGI & CO., LTD. (JP) | 1995-11-15 | — | — | EP | disclosed |
| US-5463107-A | Useful in prophylaxis and treatment of diseases caused by excessive secretion of endothelin | SHIONOGI & CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| CN-1106368-A | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO (JP) | 1995-08-09 | — | — | CN | disclosed |
| EP-0628569-A1 | Triterpene derivatives and endothelin-receptor antagonists containing the same | SHIONOGI & CO., LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |