Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ACSL1 | P33121 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.32 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955108 | 0.88 | PARP10 (0.37) | PARP10POLBPTPN1ROCK1MAP4K4 | |
| SCHEMBL8233665 | 0.77 | ERN1 (0.56) | ERN1 | |
| SCHEMBL29955933 | 0.76 | PARP10 (0.40) | PARP10POLBPTPN1ROCK1MAP4K4 | |
| SCHEMBL29955096 | 0.74 | PARP10 (0.50) | PARP10MAP4K4ERN1 | |
| SCHEMBL29954396 | 0.73 | POLB (0.36) | POLBMAP4K4 | |
| SCHEMBL29956935 | 0.72 | MAOB (0.44) | PARP10ACSL1HRH1FFAR4ACSL3 | |
| SCHEMBL29950762 | 0.72 | ERN1 (0.36) | PARP10POLBPTPN1ERN1 | |
| SCHEMBL29957323 | 0.72 | CA1 (0.36) | POLBHRH1ERN1HPGD | |
| SCHEMBL29957857 | 0.72 | ALDH1A1 (0.40) | POLBHPGD | |
| SCHEMBL29951453 | 0.71 | PARP10 (0.50) | PARP10MAP4K4ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |