Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 2/20 | 0.51 |
| ▸ | F3 | P13726 | 2/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286735 | 1.00 | CYP2A6 (0.58) | CYP2A6F11F7F3DAO | |
| SCHEMBL286843 | 0.85 | CYP2A6 (0.58) | CYP2A6F11DAOALDH1A1MAPT | |
| SCHEMBL8350514 | 0.82 | F7 (0.46) | CYP2A6F11F7F3DAO | |
| SCHEMBL8350520 | 0.82 | F7 (0.46) | CYP2A6F11F7F3DAO | |
| SCHEMBL11174139 | 0.81 | LOXL2 (0.49) | F11F7F3DAOLOXL2 | |
| SCHEMBL1335177 | 0.77 | CYP2A6 (0.58) | CYP2A6DAOALDH1A1MAPTLMNA | |
| SCHEMBL5159704 | 0.77 | CYP2A6 (0.58) | CYP2A6HRH4FLT3 | |
| SCHEMBL20391286 | 0.77 | CYP2A6 (0.58) | CYP2A6MAPTFLT3 | |
| SCHEMBL4273824 | 0.77 | CYP2A6 (0.58) | CYP2A6CYP19A1AHRNR4A2HRH4 | |
| SCHEMBL5379757 | 0.77 | CYP2A6 (0.58) | CYP2A6DAOLOXL2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139291-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |