SCHEMBL29952916

SCHEMBL29952916

O=Cc1ncc2c(n1)OCCC2

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 4/20 0.32
ACHE P22303 2/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2930804 1.00 GRM1 (0.32) GRM1ACHETP53CYP3A4MAPK1
SCHEMBL4296787 0.77 GRM1 (0.30) GRM1
SCHEMBL2933588 0.76 GRM5 (0.41) GRM1ACHETP53MAPK1SMN1; SMN2
SCHEMBL2933591 0.76 GRM5 (0.41) GRM1ACHETP53MAPK1SMN1; SMN2
SCHEMBL13114358 0.74 ACHE (0.35) GRM1ACHETP53CYP3A4MAPK1
SCHEMBL21371866 0.74 ACHE (0.32) GRM1ACHE
SCHEMBL7459009 0.74 ACHE (0.39) GRM1ACHETP53CYP3A4MAPK1
SCHEMBL2937487 0.74
SCHEMBL29957430 0.70 GRM1 (0.37) GRM1ACHETP53CYP3A4MAPK1
SCHEMBL3844482 0.67 ACHE (0.39) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed