Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.58 |
| ▸ | PIM3 | Q86V86 | 8/20 | 0.55 |
| ▸ | PIM1 | P11309 | 7/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14887044 | 0.87 | TRIM24 (0.54) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL1418447 | 0.83 | TRIM24 (0.63) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL4932467 | 0.81 | LTA4H (0.59) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL14961120 | 0.80 | MAPT (0.60) | TRIM24TRIM33PIM3PIM1KMT2A | |
| SCHEMBL23777449 | 0.78 | TRIM24 (0.47) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL13219343 | 0.78 | PIM3 (0.78) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL20673991 | 0.76 | ADRB3 (0.44) | CYP2A6KMT2AKDM4EALDH1A1DAO | |
| SCHEMBL29950589 | 0.76 | CYP2A6 (0.54) | CYP2A6IMPDH2KMT2AKDM4EMAPT | |
| SCHEMBL29954763 | 0.75 | TRIM24 (0.70) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL5418014 | 0.74 | CLEC4M (0.67) | TRIM24TRIM33PIM3PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |