Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421827 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23422001 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23421998 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23235966 | 0.80 | MEN1 (0.36) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23420924 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23422043 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL21879984 | 0.77 | ATM (0.31) | ATM | |
| SCHEMBL10579577 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL6344541 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8081105 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |