SCHEMBL23421998

SCHEMBL23421998

C=Cc1ncc(C(=O)OC)n1C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
RAB9A P51151 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPC1 O15118 2/20 0.43
MAPT P10636 1/20 0.40
KDM4E B2RXH2 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 3/20 0.34
ATM Q13315 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23421827 0.94 SMN1; SMN2 (0.41) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL23422043 0.91 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL29952967 0.85 SMN1; SMN2 (0.46) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL10579577 0.75 SMN1; SMN2 (0.52) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL23422001 0.75 SMN1; SMN2 (0.41) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL6344541 0.74 SMN1; SMN2 (0.48) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL8700542 0.74 SMN1; SMN2 (0.48) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL2228123 0.74 SMN1; SMN2 (0.48) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL8081105 0.74 SMN1; SMN2 (0.48) SMN1; SMN2RAB9AMEN1KMT2ANPC1
SCHEMBL21879877 0.73 HTT (0.47) SMN1; SMN2RAB9AMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
WO-2021106230-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2021-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB SMN1; SMN2 3261/4885RAB9A 876/4885MEN1 2667/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 SMN1; SMN2 3158/4885RAB9A 919/4885MEN1 3722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.