Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330365 | 0.86 | MAPK14 (0.34) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL29955381 | 0.81 | KDM4E (0.34) | KDM4ECYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL756337 | 0.78 | CYP1A2 (0.33) | KDM4EHTTALDH1A1TSHRCYP1A2 | |
| SCHEMBL15332807 | 0.78 | KDM4E (0.39) | KDM4EPKMHTTALDH1A1HPGD | |
| SCHEMBL939241 | 0.77 | KDM4E (0.35) | KDM4ECYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL2569093 | 0.77 | CYP1A2 (0.32) | KDM4ECYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL15330148 | 0.77 | KDM4E (0.35) | KDM4ECYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL15330438 | 0.75 | KMT2A (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29958133 | 0.74 | LMNA (0.37) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2555366 | 0.74 | KDM4E (0.33) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |