Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 14/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24086588 | 0.78 | ERN1 (0.38) | ERN1 | |
| SCHEMBL29951690 | 0.75 | TDP1 (0.38) | ERN1 | |
| SCHEMBL29957354 | 0.75 | GRIA1 (0.37) | ERN1 | |
| SCHEMBL24086660 | 0.75 | GRIA1 (0.37) | ERN1 | |
| SCHEMBL16702226 | 0.75 | LMNA (0.39) | ERN1TRIM24TRIM33 | |
| SCHEMBL29954476 | 0.75 | ERN1 (0.32) | ERN1 | |
| SCHEMBL1389512 | 0.75 | ERN1 (0.48) | ERN1TRIM24TRIM33CDK1 | |
| SCHEMBL22466186 | 0.75 | ERN1 (0.48) | ERN1TRIM24TRIM33CDK1 | |
| SCHEMBL24571167 | 0.71 | LMNA (0.39) | ERN1TRIM24TRIM33 | |
| SCHEMBL31573311 | 0.71 | TDP1 (0.42) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |