Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 8/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25873074 | 0.80 | HSD17B10 (0.38) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL20984005 | 0.75 | HSD17B10 (0.44) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22584748 | 0.75 | HSD17B10 (0.44) | HSD17B10ALDH1A1POLBCYP2A6TSHR | |
| SCHEMBL7304753 | 0.75 | HSD17B10 (0.59) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29950886 | 0.75 | HSD17B10 (0.44) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3200833 | 0.74 | HSD17B10 (0.35) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29954753 | 0.74 | MAPT (0.37) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2560798 | 0.74 | SLC2A1 (0.48) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3783762 | 0.73 | MGLL (0.43) | HSD17B10KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5432699 | 0.72 | CYP2A6 (0.46) | HSD17B10ALDH1A1HPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |