Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882038 | 0.82 | TSHR (0.83) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL177424 | 0.82 | TSHR (0.83) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL130793 | 0.81 | CA1 (0.67) | TSHRLMNARAB9ACA12CA1 | |
| SCHEMBL29948203 | 0.81 | CA1 (0.67) | TSHRLMNARAB9ACA12CA1 | |
| SCHEMBL25284690 | 0.79 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL5340855 | 0.79 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL825367 | 0.79 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL701512 | 0.79 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL9426701 | 0.79 | TSHR (0.78) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL21828892 | 0.79 | TSHR (0.62) | TSHRPOLBCASP6LMNAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |