Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957181 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL1606273 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29951155 | 0.80 | MAPT (0.49) | MEN1KMT2ALMNATP53POLB | |
| SCHEMBL3965642 | 0.80 | MAPT (0.49) | MEN1KMT2ALMNATP53POLB | |
| SCHEMBL29951367 | 0.79 | RXFP1 (0.47) | KDM4EMEN1KMT2AHCRTR1MAPT | |
| SCHEMBL411586 | 0.76 | DAO (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29955182 | 0.76 | DAO (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29951356 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8040679 | 0.73 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL3280367 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |