Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953816 | 0.88 | ALDH1A1 (0.36) | NPSR1ALDH1A1HTTEPHX2KDM4E | |
| SCHEMBL2561646 | 0.82 | TDP1 (0.38) | NPSR1ALDH1A1PLA2G2APLA2G5KDM4E | |
| SCHEMBL4937544 | 0.77 | ALDH1A1 (0.44) | NPSR1ALDH1A1PLA2G2APLA2G5EPHX2 | |
| SCHEMBL4937559 | 0.77 | ALDH1A1 (0.44) | NPSR1ALDH1A1PLA2G2APLA2G5EPHX2 | |
| SCHEMBL19197747 | 0.77 | NPSR1 (0.42) | NPSR1ALDH1A1EPHX2KDM4E | |
| Hydrochloric Acid SCHEMBL4936590 | 0.76 | ALDH1A1 (0.43) | NPSR1ALDH1A1PLA2G2APLA2G5EPHX2 | |
| Hydrochloric Acid SCHEMBL4936603 | 0.76 | ALDH1A1 (0.43) | NPSR1ALDH1A1PLA2G2APLA2G5EPHX2 | |
| SCHEMBL29954500 | 0.74 | KMT2A (0.36) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL23506609 | 0.74 | EPHX2 (0.43) | NPSR1EPHX2 | |
| SCHEMBL2562216 | 0.73 | NPSR1 (0.35) | NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |