Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | FYN | P06241 | 4/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16335197 | 1.00 | HPGD (0.37) | HPGDPTPN1MCL1ATMRAB9A | |
| SCHEMBL6886441 | 0.86 | ATM (0.39) | HPGDPTPN1MCL1ATMRAB9A | |
| SCHEMBL772019 | 0.82 | ENPP2 (0.37) | PTPN1FYNENPP2CA1CA2 | |
| SCHEMBL3316169 | 0.81 | NQO1 (0.48) | HPGDSMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL204912 | 0.81 | PTPN1 (0.38) | HPGDPTPN1MCL1ATMFYN | |
| SCHEMBL29952345 | 0.81 | NQO1 (0.48) | HPGDSMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL1918176 | 0.81 | ENPP2 (0.44) | FYNENPP2CA1CA2MAPT | |
| SCHEMBL29636771 | 0.79 | CA1 (0.50) | MCL1ENPP2CA1CA2SMN1; SMN2 | |
| SCHEMBL42032 | 0.79 | CA1 (0.50) | MCL1ENPP2CA1CA2SMN1; SMN2 | |
| SCHEMBL10271335 | 0.79 | HPGD (0.49) | HPGDATMRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |