Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550053 | 1.00 | HPGD (0.52) | HPGDNPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL29954231 | 0.94 | NPC1 (0.52) | HPGDNPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL29952096 | 0.93 | NPC1 (0.55) | HPGDNPC1RAB9ASMN1; SMN2KDM1A | |
| SCHEMBL457248 | 0.82 | NPC1 (0.50) | HPGDNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL4043511 | 0.82 | HPGD (0.64) | HPGDNPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL29951948 | 0.81 | KDM1A (0.57) | HPGDNPC1RAB9ASMN1; SMN2KDM1A | |
| SCHEMBL4191547 | 0.81 | HPGD (0.71) | HPGDNPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL29955977 | 0.79 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL15940756 | 0.79 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL19947326 | 0.78 | HPGD (0.63) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |