Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952096 | 0.89 | NPC1 (0.55) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29954231 | 0.87 | NPC1 (0.52) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29956295 | 0.83 | HPGD (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29953310 | 0.81 | HPGD (0.52) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15550053 | 0.81 | HPGD (0.52) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29951467 | 0.81 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16548438 | 0.80 | NPC1 (0.66) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20197291 | 0.80 | KDM1A (0.60) | KDM1AMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29956298 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL26085769 | 0.78 | ALDH1A1 (0.53) | KDM1AMAOANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |