SCHEMBL29953339

SCHEMBL29953339

OB(O)c1cccnc1N1CCNCC1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.56
HTR2C P28335 4/20 0.50
PLD1 Q13393 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR3E A5X5Y0 1/20 0.45
HTR3B O95264 1/20 0.45
HTR1A P08908 1/20 0.45
HTR3A P46098 1/20 0.45
HTR3D Q70Z44 1/20 0.45
HTR3C Q8WXA8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18342345 1.00 EPHX2 (0.56) EPHX2HTR2CPLD1KDM4EALDH1A1
SCHEMBL29953873 0.84 CYP1A2 (0.50) KDM4EALDH1A1
SCHEMBL15915410 0.84 CYP1A2 (0.50) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL29957554 0.83 CYP1A2 (0.49) KDM4EALDH1A1
SCHEMBL1519191 0.81 CHIA (0.52) HTR2CALDH1A1HTR3EHTR3BHTR1A
SCHEMBL29952663 0.80 CYP1A2 (0.54) KDM4E
SCHEMBL15743182 0.80 CYP1A2 (0.54) KDM4E
SCHEMBL18740245 0.79 EPHX2 (0.59) EPHX2HTR2CPLD1KDM4EALDH1A1
SCHEMBL615931 0.79 EPHX2 (0.59) EPHX2HTR2CPLD1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL29955109 0.79 CYP1A2 (0.52) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed