Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970778 | 0.84 | CYP17A1 (0.46) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL29948300 | 0.84 | CYP17A1 (0.46) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL16879643 | 0.84 | ATR (0.44) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL535514 | 0.82 | ATR (0.43) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL9939369 | 0.82 | ATR (0.46) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL12584018 | 0.81 | MAPKAPK2 (0.43) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL29364468 | 0.81 | ATR (0.42) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL1581324 | 0.81 | ATR (0.42) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL18369794 | 0.81 | ATR (0.42) | ATRP2RX3MAPKAPK2METAP1TRPA1 | |
| SCHEMBL21262226 | 0.81 | ATR (0.44) | ATRP2RX3MAPKAPK2METAP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |