Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318284 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MCL1MAPTKDM4EGAA | |
| SCHEMBL3194145 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10CYP1A2TSHR | |
| SCHEMBL70219 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MEN1DNMT1CACNA1BAPBA1 | |
| SCHEMBL29363189 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MEN1DNMT1CACNA1BAPBA1 | |
| SCHEMBL29953587 | 0.76 | JAK2 (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL21496417 | 0.76 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29953975 | 0.76 | NPC1 (0.38) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL27235544 | 0.76 | NPC1 (0.38) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL19878568 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29533264 | 0.76 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |