Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286351 | 1.00 | SLC2A1 (0.64) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL1546237 | 0.82 | SLC2A1 (0.62) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL27875451 | 0.82 | SLC2A1 (0.62) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL9000418 | 0.79 | SLC2A1 (0.58) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL25042631 | 0.78 | SLC2A1 (1.00) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL30275251 | 0.78 | SLC2A1 (1.00) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL30275111 | 0.78 | SLC2A1 (1.00) | SLC2A1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL14988861 | 0.77 | MAPT (0.56) | SLC2A1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL14988862 | 0.77 | MAPT (0.56) | SLC2A1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL20337186 | 0.77 | SLC2A1 (0.59) | SLC2A1MAPTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |