Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956830 | 0.92 | MAPT (0.67) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL14274121 | 0.88 | CASR (0.67) | MAPTKMT2AMEN1EPHX2HPGD | |
| SCHEMBL14274120 | 0.84 | CASR (0.65) | MAPTKMT2AMEN1EPHX2HPGD | |
| SCHEMBL29957192 | 0.84 | EPHX2 (0.58) | MAPTKMT2AMEN1EPHX2GAA | |
| SCHEMBL14274122 | 0.83 | CASR (0.64) | MAPTKMT2AMEN1EPHX2HPGD | |
| SCHEMBL25722908 | 0.82 | MAPT (0.75) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL29952966 | 0.82 | KMT2A (0.69) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL30493785 | 0.82 | MAPT (0.62) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL26102574 | 0.82 | MAPT (0.62) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL7828340 | 0.82 | EPHX1 (0.68) | KMT2AEPHX2SMN1; SMN2EPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |