Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952991 | 0.91 | MAPT (0.60) | EPHX2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29953432 | 0.84 | MAPT (0.64) | EPHX2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13199541 | 0.83 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL7828340 | 0.82 | EPHX1 (0.68) | EPHX2SMN1; SMN2ALDH1A1EPHX1HTT | |
| SCHEMBL5974975 | 0.82 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL29951995 | 0.81 | MAPT (0.64) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL15613891 | 0.81 | HSD17B10 (0.57) | EPHX2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27440837 | 0.80 | MAPT (0.57) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL27439714 | 0.80 | MAPT (0.57) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL27892102 | 0.80 | MAPT (0.64) | MAPTNPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |