Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331096 | 0.87 | MAPT (0.41) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL29956092 | 0.87 | KMT2A (0.48) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL15332774 | 0.85 | MAPT (0.41) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL15329773 | 0.85 | PTGS2 (0.36) | — | |
| SCHEMBL5904701 | 0.85 | BRAF (0.42) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL15331087 | 0.84 | MAPT (0.41) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL29954298 | 0.80 | SMN1; SMN2 (0.49) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL15331232 | 0.80 | KMT2A (0.45) | KMT2AMEN1HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL15332571 | 0.78 | RIPK2 (0.51) | KMT2AMEN1HSP90AA1MAPTLMNA | |
| SCHEMBL29954472 | 0.78 | CNR1 (0.33) | KMT2AMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |