Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568363 | 1.00 | NQO1 (0.61) | NQO1MAOAMGAMMAOBRXFP1 | |
| SCHEMBL29952602 | 0.84 | NQO1 (0.49) | NQO1MAOAMGAMMAOBPTPN1 | |
| SCHEMBL3364138 | 0.82 | NQO1 (0.71) | NQO1MAOAMGAMMAOBMKNK2 | |
| SCHEMBL29951008 | 0.81 | NQO1 (0.61) | NQO1PTPN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL29958053 | 0.81 | NQO1 (0.61) | NQO1MAOBALDH1A1KDM4EMEN1 | |
| SCHEMBL10436941 | 0.81 | NQO1 (0.61) | NQO1MAOBALDH1A1KDM4EMEN1 | |
| SCHEMBL29953189 | 0.81 | CA12 (0.62) | NQO1MAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL11415283 | 0.78 | NQO1 (0.64) | NQO1MAOAMAOBRXFP1ALDH1A1 | |
| SCHEMBL3912373 | 0.78 | NQO1 (0.65) | NQO1MAOAMGAMMAOBMKNK2 | |
| SCHEMBL2232638 | 0.77 | KDM4E (0.59) | NQO1MAOAMAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |