SCHEMBL29952602

SCHEMBL29952602

O=Cc1c(Cl)c2cc(Cl)ccc2oc1=O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.49
PTPN1 P18031 1/20 0.46
MAOB P27338 1/20 0.45
ADORA3 P0DMS8 3/20 0.44
ADCY1 Q08828 1/20 0.44
AHR P35869 5/20 0.44
CDC25A P30304 1/20 0.43
CDC25C P30307 1/20 0.43
MAOA P21397 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MGAM O43451 1/20 0.43
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
TTR P02766 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
TNKS O95271 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955895 0.84 CA9 (0.48) PTPN1MAOACA2CA9CA12
SCHEMBL9910631 0.84 CA9 (0.48) PTPN1MAOACA2CA9CA12
SCHEMBL29957740 0.84 MEN1 (0.56) NQO1PTPN1CDC25ACDC25CCA2
SCHEMBL11568363 0.84 NQO1 (0.61) NQO1PTPN1MAOBADCY1CDC25A
SCHEMBL29953437 0.84 NQO1 (0.61) NQO1PTPN1MAOBADCY1CDC25A
SCHEMBL17845026 0.84 MEN1 (0.56) NQO1PTPN1CDC25ACDC25CCA2
SCHEMBL3196866 0.84 CA2 (0.57) NQO1MAOBALDH1A1CA2CA9
SCHEMBL10336569 0.80 NQO1 (0.56) NQO1MAOBADORA3ADCY1AHR
SCHEMBL5273182 0.79 CA9 (0.53) NQO1MAOBADORA3MAOAALDH1A1
SCHEMBL10992566 0.77 AHR (0.47) NQO1PTPN1ADORA3ADCY1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed