Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071542 | 1.00 | LMNA (0.49) | LMNAPOLBRXFP1ATRMAOB | |
| SCHEMBL2968874 | 0.83 | ERN1 (0.42) | LMNAPOLBRXFP1ATRLCK | |
| SCHEMBL29954566 | 0.83 | ERN1 (0.42) | LMNAPOLBRXFP1ATRLCK | |
| SCHEMBL29957958 | 0.82 | LCK (0.49) | ATRLCK | |
| SCHEMBL29954888 | 0.81 | LCK (0.49) | LMNAATRSMN1; SMN2LCK | |
| SCHEMBL4069463 | 0.80 | MAOB (0.46) | LMNAMAOBSMN1; SMN2CTSSNFKB1 | |
| SCHEMBL2198998 | 0.80 | TLR2 (0.49) | LMNAPOLBATRSMN1; SMN2 | |
| SCHEMBL29954491 | 0.80 | TLR2 (0.49) | LMNAPOLBATRSMN1; SMN2 | |
| SCHEMBL3532249 | 0.78 | ATR (0.54) | LMNAPOLBRXFP1ATR | |
| SCHEMBL27289068 | 0.76 | CA12 (0.46) | LMNAPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |