Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12245650 | 1.00 | TAAR1 (0.48) | TAAR1IDO1LMNAALDH1A1AOC3 | |
| SCHEMBL4837063 | 0.82 | TAAR1 (0.35) | TAAR1IDO1LMNA | |
| SCHEMBL11366815 | 0.82 | HSPA5 (0.33) | IDO1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29956636 | 0.77 | TAAR1 (0.56) | TAAR1IDO1LMNAALDH1A1AOC3 | |
| SCHEMBL10175168 | 0.73 | TAAR1 (0.48) | TAAR1IDO1LMNAALDH1A1KMT2A | |
| SCHEMBL29956400 | 0.73 | TAAR1 (0.39) | TAAR1ALDH1A1CYP2A13 | |
| SCHEMBL29953521 | 0.73 | IDO1 (0.48) | IDO1ALDH1A1 | |
| SCHEMBL29956866 | 0.73 | PSEN1 (0.40) | IDO1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6242080 | 0.71 | IDO1 (0.50) | TAAR1IDO1LMNAAOC3CYP1A2 | |
| SCHEMBL376960 | 0.71 | TAAR1 (0.46) | TAAR1LMNAALDH1A1KMT2ACYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |