Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952198 | 0.85 | TAAR1 (0.55) | TAAR1GAAKDM4ESMN1; SMN2HTT | |
| SCHEMBL13167100 | 0.85 | EED (0.37) | TAAR1GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30554696 | 0.80 | KDM1A (0.43) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29955123 | 0.75 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL4837063 | 0.75 | TAAR1 (0.35) | TAAR1GAACES2CES1 | |
| SCHEMBL29953492 | 0.73 | TAAR1 (0.48) | TAAR1ALDH1A1CYP2A13 | |
| SCHEMBL12245650 | 0.73 | TAAR1 (0.48) | TAAR1ALDH1A1CYP2A13 | |
| SCHEMBL29956889 | 0.72 | MPO (0.35) | TAAR1GAACYP2A13 | |
| SCHEMBL5205493 | 0.69 | TAAR1 (0.46) | TAAR1GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7701701 | 0.69 | TAAR1 (0.52) | TAAR1GAAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |