Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 3/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586488 | 1.00 | TTK (0.62) | TTKITKAURKBTRPA1SCN5A | |
| SCHEMBL4514654 | 0.87 | TTK (0.48) | TTKITKMAPK10RIPK1 | |
| SCHEMBL3709667 | 0.80 | TTK (0.61) | TTKITKAURKBTRPA1GSK3B | |
| SCHEMBL3709670 | 0.80 | TTK (0.61) | TTKITKAURKBTRPA1GSK3B | |
| SCHEMBL15304355 | 0.78 | ITK (0.46) | TTKITKCHEK1 | |
| SCHEMBL29955085 | 0.78 | ITK (0.46) | TTKITKCHEK1 | |
| SCHEMBL586433 | 0.77 | TTK (1.00) | TTKAURKBCHEK1 | |
| SCHEMBL586434 | 0.77 | TTK (1.00) | TTKAURKBCHEK1 | |
| SCHEMBL1799976 | 0.76 | PDPK1 (0.55) | TTKITKAURKBTRPA1SCN5A | |
| SCHEMBL3538242 | 0.76 | TTK (0.54) | TTKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |