Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781726 | 0.81 | HSD17B1 (0.45) | MGLLMAPTKDM4ELMNAPKM | |
| SCHEMBL3786148 | 0.79 | GAA (0.54) | MGLLMAPTKDM4ELMNAPKM | |
| SCHEMBL11888379 | 0.76 | HSD17B1 (0.47) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL114000 | 0.75 | HSD17B1 (0.47) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL10205947 | 0.74 | PLA2G10 (0.49) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL23447125 | 0.73 | CYP1A2 (0.42) | MAPTKDM4ERAB9AHSD17B1ALDH1A1 | |
| SCHEMBL6232939 | 0.72 | MAPT (0.56) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL13739868 | 0.72 | MAPT (0.40) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL6812091 | 0.72 | MAPT (0.40) | MAPTKDM4ELMNAPKMRXFP1 | |
| SCHEMBL31181950 | 0.72 | GAA (0.54) | MAPTKDM4ELMNAPKMRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |