Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | APOL1 | O14791 | 9/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557351 | 0.89 | GSK3A (0.37) | GSK3BGSK3AAPOL1 | |
| SCHEMBL29955474 | 0.89 | GSK3B (0.37) | GSK3BGSK3AAPOL1ALOX5TNKS | |
| SCHEMBL15331395 | 0.88 | AR (0.35) | GSK3BALOX5TNKSTNKS2AR | |
| SCHEMBL2558807 | 0.88 | APOL1 (0.37) | GSK3BGSK3AAPOL1ALOX5TNKS2 | |
| SCHEMBL2577085 | 0.87 | APOL1 (0.40) | GSK3BGSK3AAPOL1 | |
| SCHEMBL15330747 | 0.86 | MAP2 (0.42) | GSK3BAPOL1ALOX5TNKSTNKS2 | |
| SCHEMBL15331396 | 0.86 | TNKS (0.39) | GSK3BGSK3AAPOL1ALOX5TNKS | |
| SCHEMBL2579477 | 0.86 | APOL1 (0.39) | GSK3BGSK3AAPOL1 | |
| SCHEMBL15332576 | 0.84 | GSK3A (0.39) | GSK3BGSK3AAPOL1CNR1 | |
| SCHEMBL15330874 | 0.84 | CNR1 (0.40) | GSK3BGSK3AALOX5TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |