Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953275 | 0.92 | KMT2A (0.54) | KDM4ESMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL29955215 | 0.88 | MEN1 (0.53) | KDM4EHTTMEN1KMT2APOLB | |
| SCHEMBL2551665 | 0.82 | KDM4E (0.48) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7824542 | 0.80 | MEN1 (0.72) | KDM4ESMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL13901436 | 0.80 | KMT2A (0.74) | KDM4EHTTMEN1KMT2ACYP2C19 | |
| SCHEMBL29953645 | 0.77 | KDM4E (0.40) | KDM4ESMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL29951744 | 0.76 | CYP2C19 (0.56) | KDM4ESMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL29951552 | 0.74 | LPAR2 (0.55) | KDM4ESMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL29953387 | 0.73 | AKR1B1 (0.39) | KDM4ESMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL11887605 | 0.72 | MEN1 (0.57) | KDM4EHTTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |