Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.35 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953387 | 0.86 | AKR1B1 (0.39) | KDM4EGAAKMT2AAKR1B10UGT1A9 | |
| SCHEMBL29955140 | 0.78 | NR3C1 (0.40) | KDM4EPTGES2APEX1GAAKMT2A | |
| SCHEMBL29953554 | 0.77 | KDM4E (0.63) | KDM4EHTTKMT2APOLBMEN1 | |
| SCHEMBL29953275 | 0.75 | KMT2A (0.54) | KDM4EHTTGAAKMT2APOLB | |
| SCHEMBL29955119 | 0.75 | CXCL8 (0.40) | KDM4EHTTKMT2AMT-CO2TTR | |
| SCHEMBL29955215 | 0.73 | MEN1 (0.53) | KDM4EHTTKMT2APOLBMEN1 | |
| SCHEMBL29955167 | 0.70 | NR3C1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL2551665 | 0.68 | KDM4E (0.48) | KDM4EKMT2APOLBMEN1TSHR | |
| SCHEMBL1122639 | 0.66 | PTK2B (0.49) | KDM4EKMT2AAKR1B10UGT1A9TRPA1 | |
| SCHEMBL27770371 | 0.66 | HTT (0.36) | KDM4EHTTKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |