Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177442 | 0.91 | KMT2A (0.61) | HDAC1HDAC6LMNATSHRALDH1A1 | |
| SCHEMBL25138742 | 0.89 | HDAC1 (0.71) | HDAC1HDAC6LMNALIMK1LIMK2 | |
| SCHEMBL1004019 | 0.85 | HDAC1 (0.71) | HDAC1HDAC6LMNALIMK1LIMK2 | |
| SCHEMBL133138 | 0.85 | HPGD (0.58) | LMNAALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL257636 | 0.83 | KMT2A (0.62) | HDAC1HDAC6LIMK1LIMK2TSHR | |
| SCHEMBL3455861 | 0.81 | HDAC1 (0.67) | HDAC1HDAC6LMNALIMK1LIMK2 | |
| SCHEMBL3178210 | 0.80 | HDAC1 (0.65) | HDAC1HDAC6LMNALIMK1LIMK2 | |
| SCHEMBL257889 | 0.79 | NPC1 (0.63) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8359492 | 0.78 | KMT2A (0.76) | HDAC1HDAC6LMNATSHRALDH1A1 | |
| SCHEMBL3836681 | 0.77 | LMNA (0.72) | HDAC1HDAC6LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |