Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954336 | 0.85 | ERN1 (0.48) | ERN1CDK8 | |
| SCHEMBL2556119 | 0.81 | ERN1 (0.41) | ERN1 | |
| SCHEMBL29951315 | 0.81 | ERN1 (0.66) | ERN1CDK8SMN1; SMN2ALDH1A1 | |
| SCHEMBL29955952 | 0.81 | ERN1 (0.81) | ERN1CDK8 | |
| SCHEMBL2556740 | 0.79 | ERN1 (0.61) | ERN1ALDH1A1 | |
| SCHEMBL29957068 | 0.79 | ERN1 (0.61) | ERN1SMN1; SMN2 | |
| SCHEMBL2560703 | 0.78 | ERN1 (0.62) | ERN1 | |
| SCHEMBL13626333 | 0.77 | SMYD2 (0.61) | CDK8SMN1; SMN2ALDH1A1SMYD2 | |
| SCHEMBL24720336 | 0.76 | HDAC1 (0.46) | ERN1CDK8SMN1; SMN2 | |
| SCHEMBL13702348 | 0.75 | CDK8 (0.56) | ERN1CDK8SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |