Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.61 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954336 | 0.82 | ERN1 (0.48) | ERN1BRD4CREBBP | |
| SCHEMBL2556740 | 0.81 | ERN1 (0.61) | ERN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29955051 | 0.81 | ERN1 (0.72) | ERN1SMYD3NPC1RAB9AMEN1 | |
| SCHEMBL29951997 | 0.81 | ERN1 (0.88) | ERN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29953590 | 0.79 | ERN1 (0.55) | ERN1SMN1; SMN2 | |
| SCHEMBL2560703 | 0.77 | ERN1 (0.62) | ERN1 | |
| SCHEMBL27769316 | 0.76 | KAT6A (0.55) | BRD4CREBBPSMYD3NPC1RAB9A | |
| SCHEMBL12767105 | 0.76 | ERN1 (1.00) | ERN1NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10094380 | 0.73 | BRD4 (0.52) | BRD4CREBBPSMYD3NPC1RAB9A | |
| SCHEMBL15730263 | 0.72 | MAPK14 (0.56) | BRD4CREBBPSMYD3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |