Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924032 | 0.83 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4773388 | 0.80 | ALDH1A1 (0.78) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22001460 | 0.78 | NPC1 (0.74) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29956631 | 0.78 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15333053 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17113969 | 0.78 | AKT2 (0.54) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29951865 | 0.76 | NPC1 (0.52) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28393023 | 0.75 | AKT2 (0.46) | NPC1RAB9AAKT2HDAC1 | |
| SCHEMBL8253610 | 0.74 | AKT2 (0.48) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13407632 | 0.74 | AKT2 (0.48) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |