Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 2/20 | 0.50 |
| ▸ | MERTK | Q12866 | 2/20 | 0.50 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577968 | 0.82 | EGFR (0.52) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL2943473 | 0.82 | TYRO3 (0.50) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL14454203 | 0.80 | TYRO3 (0.51) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL28372825 | 0.79 | KDM4E (0.54) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL11988204 | 0.78 | TYRO3 (0.50) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL951715 | 0.77 | KDM4E (0.49) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL2948725 | 0.76 | MAPT (0.59) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL19425648 | 0.75 | KDM4E (0.45) | TYRO3MERTKGAS6KDM4EGAA | |
| SCHEMBL3323149 | 0.75 | FYN (0.49) | KDM4ENPC1RAB9ALMNANPSR1 | |
| SCHEMBL247578 | 0.73 | KCNH3 (0.39) | TYRO3MERTKGAS6POLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |