Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994957 | 0.88 | KDM4E (0.39) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL1042131 | 0.88 | KDM4E (0.39) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL15674823 | 0.86 | EGFR (0.48) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL986881 | 0.84 | CYP1A2 (0.55) | KDM4EKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL29950647 | 0.84 | CYP1A2 (0.55) | KDM4EKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL319585 | 0.82 | ENPP2 (0.47) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29588618 | 0.82 | ENPP2 (0.47) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4870587 | 0.81 | KDM4E (0.44) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL14029250 | 0.80 | PTGDR2 (0.52) | KDM4EHTTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL15329658 | 0.79 | KMT2A (0.40) | KDM4EHTTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |