Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12450080 | 1.00 | ERN1 (0.52) | ERN1SRCRAPGEF4NPSR1ALDH1A1 | |
| SCHEMBL14033478 | 0.82 | ERN1 (0.52) | ERN1SRCNPSR1ALDH1A1KDM4E | |
| SCHEMBL10325195 | 0.82 | ERN1 (0.52) | ERN1SRCRAPGEF4NPSR1ALDH1A1 | |
| SCHEMBL4746714 | 0.79 | ERN1 (0.39) | ERN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29955919 | 0.79 | ERN1 (0.39) | ERN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8277341 | 0.78 | ERN1 (0.48) | ERN1SRCNPSR1ALDH1A1KDM4E | |
| SCHEMBL14726039 | 0.78 | ERN1 (0.59) | ERN1SRC | |
| SCHEMBL13855816 | 0.78 | ERN1 (0.72) | ERN1 | |
| SCHEMBL12135681 | 0.78 | ERN1 (0.48) | ERN1SRCRAPGEF4NPSR1ALDH1A1 | |
| SCHEMBL585592 | 0.76 | ERN1 (0.61) | ERN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |