Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.61 |
| ▸ | CES2 | O00748 | 6/20 | 0.48 |
| ▸ | CES1 | P23141 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295466 | 0.79 | ERN1 (0.43) | ERN1CES2CES1CA1CA2 | |
| SCHEMBL3725574 | 0.78 | ERN1 (0.44) | ERN1CES2CES1CA1CA2 | |
| SCHEMBL24014278 | 0.76 | ERN1 (0.57) | ERN1CES2CES1KDM4EALDH1A1 | |
| SCHEMBL3066902 | 0.76 | ERN1 (0.47) | ERN1CES2CES1 | |
| SCHEMBL12450080 | 0.76 | ERN1 (0.52) | ERN1KDM4EALDH1A1 | |
| SCHEMBL20088346 | 0.76 | ERN1 (0.57) | ERN1CES2CES1KDM4EALDH1A1 | |
| SCHEMBL332788 | 0.76 | ERN1 (0.47) | ERN1CES2CES1KDM4EALDH1A1 | |
| SCHEMBL21949881 | 0.76 | ERN1 (0.38) | ERN1CES2CES1 | |
| SCHEMBL20798249 | 0.76 | ERN1 (0.52) | ERN1 | |
| SCHEMBL767476 | 0.76 | ERN1 (0.47) | ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143598-B | High-entropy carbon quantum dot nanomaterial and preparation method and application thereof | 中南大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118459420-A | Thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118459422-A | Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118085334-A | High-tensile swelling-resistant polyvinyl alcohol-based hydrogel and preparation method and application thereof | 国科广化(南雄)新材料研究院有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117143598-A | High-entropy carbon quantum dot nanomaterial and preparation method and application thereof | 中南大学 | 2023-12-01 | — | — | CN | claimed |
| CN-115092909-B | High-concentration fluorine-doped carbon dot and preparation method thereof | 中南大学 | 2023-06-09 | — | — | CN | claimed |
| CN-115092909-A | High-concentration fluorine-doped carbon dot and preparation method thereof | 中南大学 | 2022-09-23 | — | — | CN | claimed |
| US-20110236400-A1 | TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION | 2011-09-29 | — | — | US | claimed |
| CN-101754960-A | tetrahydropyranochromene gamma-secretase inhibitors | SCHERING CORP | 2010-06-23 | — | — | CN | claimed |
| WO-2009008980-A2 | TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | claimed |
| EP-4741389-A1 | KAT6 INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-20260062406-A1 | Benzisoxazole Sulfonamide Derivatives | PFIZER (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4299135-B1 | BENZISOXAZOLE SULFONAMIDE DERIVATIVES | PFIZER (US) | 2025-08-06 | — | — | EP | disclosed |
| US-12371425-B2 | Benzisoxazole sulfonamide derivatives | PFIZER INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | GENENTECH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20030105106-A1 | 5-HT receptor ligands and uses thereof | CHIANG PHOEBE (US) | 2003-06-05 | — | — | US | disclosed |
| WO-2003000663-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000666-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371425-B2 | Benzisoxazole sulfonamide derivatives | BRIX1, RB1, BCR | ERN1 1914/4885CES2 2887/4885CES1 1555/4885 |
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | RB1, CCNE2, RPS3A | ERN1 2346/4885CES2 3471/4885CES1 2941/4885 |
| US-20030105106-A1 | 5-HT receptor ligands and uses thereof | HTR1A, HTR2A, HTR5A | ERN1 4527/4885CES2 366/4885CES1 1255/4885 |
| US-20260062406-A1 | Benzisoxazole Sulfonamide Derivatives | KAT8, KAT5, KAT7 | ERN1 2844/4885CES2 1880/4885CES1 1649/4885 |
| US-20110236400-A1 | TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS | BACE1, BACE2, APP | ERN1 1941/4885CES2 656/4885CES1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.