Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710473 | 0.77 | LRRK2 (0.44) | AURKAPARP1LOXL3LOXL2CDK4 | |
| SCHEMBL6246075 | 0.77 | MAPK14 (0.66) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL4411780 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL28322523 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL858414 | 0.76 | IMPDH2 (0.50) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL29952302 | 0.75 | ADORA2A (0.47) | ADORA2AADORA1MAPK13MAPK12MAPK11 | |
| SCHEMBL1780573 | 0.75 | MAPK13 (0.59) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL857451 | 0.73 | ADORA2A (0.48) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL29952292 | 0.72 | ADORA2A (0.50) | ADORA2AADORA1PADI4MAPK13MAPK12 | |
| SCHEMBL8692300 | 0.71 | GRIN2D (0.73) | ADORA2AADORA1PADI4AURKAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |