Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732892 | 0.83 | POLB (0.47) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27979898 | 0.80 | POLB (0.45) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1865928 | 0.80 | KMT2A (0.51) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16013353 | 0.78 | PKM (0.51) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1107562 | 0.78 | PKM (0.51) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1107514 | 0.78 | PKM (0.55) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1862274 | 0.78 | KMT2A (0.51) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28282664 | 0.76 | PKM (0.50) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1860255 | 0.76 | PKM (0.61) | PKMKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16943108 | 0.75 | POLB (0.49) | PKMKMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |