Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082005 | 1.00 | ERN1 (0.68) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL7031594 | 0.88 | ERN1 (0.78) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL6268566 | 0.86 | ERN1 (0.52) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL10088517 | 0.81 | ERN1 (0.46) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL23442397 | 0.81 | ERN1 (0.73) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL829755 | 0.81 | ERN1 (1.00) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL10331731 | 0.80 | ERN1 (0.45) | ERN1CYP3A4HPGDPOLBKMT2A | |
| SCHEMBL869070 | 0.79 | CYP3A4 (0.48) | ERN1CYP3A4HPGDKMT2AMAPT | |
| SCHEMBL15348517 | 0.79 | ERN1 (0.66) | ERN1CYP3A4HPGDTRIM24TYR | |
| SCHEMBL30294862 | 0.79 | ERN1 (0.96) | ERN1CYP3A4HPGDTRIM24TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |