SCHEMBL829755

SCHEMBL829755

COc1cc(O)c(C=O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 1.00
LMNA P02545 1/20 0.54
CYP3A4 P08684 2/20 0.53
USP2 O75604 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CHRNA7 P36544 1/20 0.52
TRIM24 O15164 2/20 0.50
TRIM33 Q9UPN9 2/20 0.50
TYR P14679 1/20 0.50
ABCG2 Q9UNQ0 3/20 0.47
ALDH1A1 P00352 3/20 0.47
AURKA O14965 1/20 0.47
AOX1 Q06278 1/20 0.46
HPGD P15428 1/20 0.46
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30294862 0.98 ERN1 (0.96) ERN1LMNACYP3A4USP2MAPK1
SCHEMBL7031594 0.88 ERN1 (0.78) ERN1LMNACYP3A4USP2MAPK1
SCHEMBL8704272 0.87 ERN1 (0.77) ERN1MAPK1CHRNA7TRIM24TRIM33
SCHEMBL29459677 0.86 ERN1 (0.76) ERN1CYP3A4TRIM24TRIM33TYR
SCHEMBL1002616 0.86 ERN1 (0.76) ERN1CYP3A4TRIM24TRIM33TYR
2,4,6-Trimethoxybenzaldehyde SCHEMBL28687256 0.86 ERN1 (0.75) ERN1LMNACYP3A4USP2MAPK1
2,4,6-Trimethoxybenzaldehyde SCHEMBL34873 0.86 ERN1 (0.74) ERN1LMNACYP3A4ABCG2ALDH1A1
SCHEMBL23442397 0.85 ERN1 (0.73) ERN1LMNACYP3A4USP2MAPK1
SCHEMBL19971990 0.84 ERN1 (0.70) ERN1LMNACYP3A4USP2MAPK1
2,4,6-Trimethoxybenzaldehyde SCHEMBL28687257 0.84 ERN1 (0.71) ERN1LMNACYP3A4ABCG2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
CN-117209741-A Preparation method of Schiff base catalyst and preparation method of polyglycolic acid 中国科学院长春应用化学研究所 2023-12-12 CN claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO claimed
CN-111116663-A Flame-retardant curing agent containing phosphazene/aromatic imine composite structure and preparation method thereof 华南理工大学 2020-05-08 CN claimed
EP-3562815-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF - LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT Global Chemical Public Company Limited (TH) 2019-11-06 EP claimed
WO-2018124978-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF δ- LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2018-07-05 WO claimed
CN-103249455-A Process for dyeing keratin fibres using hydroxybenzaldehyde derivatives, oxidizing agents and alkalinizing agents in the presence of heat OREAL 2013-08-14 CN claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
EP-4737508-A1 CHEMICAL RECYCLING METHOD FOR MIXED WASTE POLYMERS Korea Research Institute of Chemical Technology (KR) 2026-05-06 EP disclosed
US-12612389-B2 Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2026-04-28 US disclosed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US disclosed
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 US disclosed
WO-2025090658-A2 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-05-01 WO disclosed
US-4999429-A Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives ETHYL CORPORATION (US) 1991-03-12 US disclosed
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US disclosed
EP-0096647-B1 A METHOD FOR PREPARING A POLYMER CONTAINING PENDANT UNSATURATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-10-29 EP disclosed
US-4446284-A Method for preparing a polymer containing pendant unsaturation THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-05-01 US disclosed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF CDK2, CDK20, CDK1 ERN1 1389/4885LMNA 1059/4885CYP3A4 2478/4885
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 ERN1 622/4885LMNA 719/4885CYP3A4 52/4885
US-12612389-B2 Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same TUBB3, TUBA1C, ACIN1 ERN1 2354/4885LMNA 365/4885CYP3A4 2693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.